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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
COPS2
All Species:
43.03
Human Site:
Y159
Identified Species:
59.17
UniProt:
P61201
Number Species:
16
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P61201
NP_001137359.1
443
51597
Y159
N
T
K
L
G
K
L
Y
L
E
R
E
E
Y
G
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001089276
443
51433
Y159
N
T
K
L
G
K
L
Y
L
E
R
E
E
Y
G
Dog
Lupus familis
XP_862009
444
51751
Y159
N
T
K
L
G
K
L
Y
L
E
R
E
E
Y
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8BG32
422
47418
H148
K
R
Y
Q
E
A
L
H
L
G
S
Q
L
L
R
Rat
Rattus norvegicus
P61203
443
51578
Y159
N
T
K
L
G
K
L
Y
L
E
R
E
E
Y
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521692
705
77929
Y406
N
T
K
L
G
K
L
Y
L
E
R
E
E
Y
G
Chicken
Gallus gallus
NP_001026767
443
51677
Y159
N
T
K
L
G
K
L
Y
L
E
R
E
E
Y
G
Frog
Xenopus laevis
Q6IR75
441
51318
Y157
N
T
K
L
G
K
L
Y
L
E
R
E
E
Y
G
Zebra Danio
Brachydanio rerio
Q6IQT4
443
51553
Y159
N
T
K
L
G
K
L
Y
L
E
R
E
E
F
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q94899
444
51508
Y160
N
T
K
L
G
K
L
Y
F
D
R
S
D
F
T
Honey Bee
Apis mellifera
XP_392587
444
51537
Y160
N
T
K
L
G
K
L
Y
F
D
R
S
D
F
N
Nematode Worm
Caenorhab. elegans
O01422
495
56762
F156
N
T
K
L
G
K
L
F
F
D
L
H
E
F
T
Sea Urchin
Strong. purpuratus
XP_780196
444
51783
Y160
N
T
K
L
G
K
L
Y
Y
D
R
E
E
F
N
Poplar Tree
Populus trichocarpa
XP_002330981
439
51362
W155
N
L
K
L
C
K
I
W
F
G
M
G
E
Y
G
Maize
Zea mays
NP_001149870
438
51327
W155
N
L
K
L
C
K
I
W
F
D
I
G
E
Y
G
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8W207
439
51168
W155
N
L
K
L
C
N
I
W
F
D
I
G
E
Y
R
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7SI58
490
56940
L162
N
I
K
L
A
R
L
L
L
D
R
K
D
Y
H
Conservation
Percent
Protein Identity:
100
N.A.
98.6
99.3
N.A.
23
100
N.A.
53.9
99.7
98.8
99.3
N.A.
83.7
86.4
57.7
85.5
Protein Similarity:
100
N.A.
98.8
99.3
N.A.
43.1
100
N.A.
57.8
99.7
99.3
100
N.A.
91.4
93.4
72.9
92.1
P-Site Identity:
100
N.A.
100
100
N.A.
13.3
100
N.A.
100
100
100
93.3
N.A.
60
60
53.3
73.3
P-Site Similarity:
100
N.A.
100
100
N.A.
26.6
100
N.A.
100
100
100
100
N.A.
80
80
73.3
86.6
Percent
Protein Identity:
64.1
64.1
N.A.
60.5
N.A.
45.7
Protein Similarity:
80.1
80.3
N.A.
79
N.A.
65.3
P-Site Identity:
46.6
46.6
N.A.
33.3
N.A.
46.6
P-Site Similarity:
60
66.6
N.A.
53.3
N.A.
73.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
6
6
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
18
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
42
0
0
18
0
0
% D
% Glu:
0
0
0
0
6
0
0
0
0
48
0
53
77
0
0
% E
% Phe:
0
0
0
0
0
0
0
6
36
0
0
0
0
30
0
% F
% Gly:
0
0
0
0
71
0
0
0
0
12
0
18
0
0
59
% G
% His:
0
0
0
0
0
0
0
6
0
0
0
6
0
0
6
% H
% Ile:
0
6
0
0
0
0
18
0
0
0
12
0
0
0
0
% I
% Lys:
6
0
95
0
0
83
0
0
0
0
0
6
0
0
0
% K
% Leu:
0
18
0
95
0
0
83
6
59
0
6
0
6
6
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
6
0
0
0
0
% M
% Asn:
95
0
0
0
0
6
0
0
0
0
0
0
0
0
12
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
6
0
0
0
0
0
0
0
6
0
0
0
% Q
% Arg:
0
6
0
0
0
6
0
0
0
0
71
0
0
0
12
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
6
12
0
0
0
% S
% Thr:
0
71
0
0
0
0
0
0
0
0
0
0
0
0
12
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
18
0
0
0
0
0
0
0
% W
% Tyr:
0
0
6
0
0
0
0
65
6
0
0
0
0
65
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _